Here, we report that resveratrol is a potent inhibitor of quinone reductase 2 (QR2) activity in vitro with a dissociation constant of 35 nM and show that it ...
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Dec 4, 2015 · A wide range of planar aromatic compounds bind NQO2, and we have identified three DNA-intercalating agents [ethidium bromide, acridine orange ( ...
Mar 30, 2016 · Together, this study shows that reduced NQO2 has structural and electrostatic properties that yield a preference for binding of planar, aromatic ...
Ribosyldihydronicotinamide dehydrogenase [quinone] Details. Keywords, Oxidoreductase/oxidoreductase Inhibitor / quinone reductase 2 / acridine orange ...
Dec 2, 2021 · The antidote effect of quinone oxidoreductase 2 inhibitor against paraquat-induced toxicity in vitro and in vivo. Br. J. Pharmacol. 2013;168 ...
Mar 1, 2019 · (2013) The antidote effect of quinone oxidoreductase 2 inhibitor against paraquat-induced toxicity in vitro and in vivo. Br J Pharmacol 168 ...
Oxidized quinone reductase 2 in complex with acridine orange · Ribosyldihydronicotinamide dehydrogenase [quinone] Details · Oxidoreductase/Inhibitor / quinone ...
Mar 25, 2004 · This obligate two-electron mechanism contrasts with many other cellular reductases and allows QR1 to divert quinones from one-electron ...
Nov 18, 2021 · A redox cycle with complex II prioritizes sulfide quinone oxidoreductase-dependent H2S oxidation ... 2S oxidation, which is inhibited by NBD-Cl.